Enteral stenting for gastric outlet obstruction and afferent limb syndrome following pancreaticoduodenectomy

Authors Wilson T. Kwong, Syed M. Fehmi, Andrew M. Lowy, Thomas J. Savides.


Background Obstruction of the afferent or efferent limbs of a gastrojejunal anastomosis is a potential complication after pancreaticoduodenectomy (PD) resulting in either gastric outlet obstruction or afferent limb syndrome. The use of self-expanding metal stents for the management of anastomotic strictures after resection of pancreatic cancer has not been well studied. We present four such cases and review published data regarding this population.

Methods Retrospective chart review and literature search. Outcomes were summarized with descriptive statistics.

Results At our institution, 4 patients underwent metal stent placement for gastrojejunal obstruction after PD for pancreatic cancer. Enteral stents were placed in two patients across the afferent limb, in one patient across the efferent limb, and in another patient across both limbs. Similar cases in the literature revealed that the anastomotic stricture was malignant in 26 of 27 cases. Clinical improvement occurred in 88%. Afferent limb syndrome was successfully treated in 5 of 6 cases. Median survival was 3.5 months after stent placement.

Conclusions Effective palliation of both gastric outlet obstruction and afferent limb syndrome after PD can be provided with enteral stenting. Gastrojejunal strictures after PD for pancreatic cancer are usually malignant with median survival of 3.5 months after stent placement.

Keywords Stent, pancreaticoduodenectomy, gastric outlet obstruction, afferent limb syndrome, pancreatic cancer

Ann Gastroenterol 2014; 27 (4): 413-417

Case Reports